If you have been prescribed Ibrance (palbociclib) as part of your cancer treatment, you surely have a whole host of questions as to what to expect. First off, let’s just acknowledge how far medical science has come—it is simply amazing we have targeted therapies like Ibrance working to slow the growth of certain cancers. Still, like with most medications, Ibrance does have its side effects. Knowing them will help you tread on your journey of treatment with confidence. Here’s a simple rundown of the potential side effects and what you need to know of it.
1. Fatigue: The Energy Thief
Feeling very tired? Fatigue is one of the most common side effects of Ibrance. It’s not your average “I didn’t sleep well” tiredness—it’s more like your body demanding a time-out.
How to Cope:
- Rest strategically: Short naps and pacing yourself can help.
- Stay active: Gentle exercises like walking or yoga might sound counterintuitive, but they can actually boost your energy levels.
- Hydrate and eat well: Balanced meals and plenty of water can work wonders.
2. Low Blood Cell Counts: The Hidden Effect
Ibrance can have an impact on your bone marrow, where your blood cells are made. This can result in a low level of white blood cells (neutropenia), red blood cells (anemia), or platelets. Low white blood cells may predispose to infections, and shortness of breath or dizziness caused by anemia.
What to Monitor For:
- Frequent infections, such as colds or fevers.
- Feeling unusually weak or out of breath.
How to Cope:
- Regular check-ups: Your doctor will monitor your blood counts during treatment.
- Be proactive: Wash your hands often and avoid crowded places to reduce infection risks.
- Talk to your doctor: If you’re feeling extra run-down, they might adjust your dose or recommend supportive treatments.
3. Hair Thinning: Not as Harsh as Chemo Hair Loss
It’s not that often that patients using Ibrance report losing their hair, but hair loss is certainly a possibility. It’s as if you woke up having a terrible hair day, but it wants to become your permanent bad hair day.
How to Cope:
- Dress with care: Mild shampoo and avoid heat styling.
- Dress for the occasion: Scarves, hats, and fun wigs are sure to add some zest to the look.
- The hair will grow back: Everyone typically finds their hair returns to normal after treatment.
4. Bad Stomach: The Unwanted Visitor
You may also experience nausea, vomiting, or constipation during Ibrance treatment. Of course, these side effects are very annoying, but most of them can be controlled.
- Eat smart: Consider eating small & regular meals, and give up greasy or spicy food.
- Hydrate yourself: Drink water, herbal teas, or clear soups.
- Inform your doctor: Your health care provider may prescribe anti-nausea medications, if necessary.
5. Ulcers Mouth: A Little Nuisance
Sometimes mouth sores appear, also known as oral mucositis. They make it uncomfortable to eat or drink, but they are generally temporary.
Coping Tips:
- Rinse often: Rinsing frequently with a mild saltwater solution can help soothe your mouth.
- Opt for soft foods: Yogurt, soups, mashed potatoes—whatever is easy to swallow.
- Avoid irritants: Steer clear of spicy or acidic foods until your mouth heals
6. Changing Appetite: Food Mood Swings
You may find you are not as hungry as you typically are—or that your cravings have gone awry. Changes in appetite are common for people on Ibrance.
Helpful Tips:
- Snack frequently: Keep healthy snack choices like nuts, fruits, or cheese close.
- Make it taste good: If the food you are eating isn’t sounding appealing, then only focus on foods you do enjoy.
- Fuel your body: A smoothie or other meal replacement drink can help on low-appetite days.
7. Skin and Nail Changes
Ibrance may cause you to experience dry or sensitive skin, and also trigger changes in your nails, such as brittleness or discoloration.
Tips to Deal:
- Moisturize: Apply a gentle, chemical-free moisturizer to hydrate your skin.
- Protect yourself: Use sunscreen and avoid harsh chemicals.
- Be patient: Most changes tend to fade with treatment.
When to Call Your Doctor
All side effects are mild and controllable, but some might need more attention.
- A temperature over 100.4°F (38°C).
- Severe or prolonged diarrhea, nausea, or vomiting.
- Unusual bruising or bleeding.
- Chest pain, shortness of breath, or swelling.
Why it’s Worth It
Side effects can be difficult but remember why you are on Ibrance in the first place. The medication is working hard to slow the growth of your cancer, and it is buying you time to focus on what really matters.
Every patient will not experience the same effects from the treatment; therefore, discuss any issues you may face with your physician. Together, you can work out a plan that helps make your treatment as smooth as possible.
The Bottom Line
Side effects are part of the journey, but with the right support and strategies, they can be well managed during your fight against skin cancer or any other kind of cancer. Remember, you are not alone—your medical team is there to guide you through this process.
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